ADENOVIRUSES USING THE CANCER MARKER EPHA2 AS A RECEPTOR IN VITRO AND IN VIVO BY GENETIC LIGAND INSERTION INTO DIFFERENT CAPSID SCAFFOLDS.

Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds.

Adenoviral gene therapy and oncolysis would critically benefit from targeted cell entry by genetically modified capsids.This requires both the ablation of native adenovirus tropism and the identification of ligands that remain functional in virus context.Here, Console Cable we establish cell type-specific entry of HAdV-5-based vectors by genetic li

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Drug-Related Deaths Among Young People Involved in The Criminal Justice System: A Whole-Population Multi-Sectoral Data Linkage Study

Introduction Drug-related death is substantially higher in formerly incarcerated adults compared to the general population.Despite this, remarkably little is known about the epidemiology of drug-related death among justice-involved adolescents.A richer understanding of drug-related mortality in justice-involved Pepper Shakers young people is essent

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Studies in the liverwort genus Fossombronia (Metzgeriales) from southern Africa. 6. New species from Lesotho, Swaziland and Mpumalanga and new records from Lesotho

Two new species of Fossombronia are described: F.angulifolia Perold from Lesotho and F.swaziensis Soccer - Goalie - Gloves Perold from Swaziland and Mpumalanga.F.angulifolia is characterised by erect or semi-erect, 2-4-lobed, angular leaves, by mostly incompletely reticulate spores and by rather short elaters F.swaziensis can be recognised by large

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